There’s a difference between a bad headache and a migraine that takes over your life.
You cancel plans. You darken the room. You wait for it to pass.
But sometimes it doesn’t.
If you’re in Orange County or Los Angeles dealing with severe, chronic, or prolonged migraines, including status migrainosus, oral medications may not be enough to interrupt the cycle.
Migraines are complex neurological events involving:
Once a migraine cycle becomes established, especially in chronic or treatment-resistant cases, it may require more than oral triptans or standard rescue medications.
Dihydroergotamine (DHE) has been used for decades in the treatment of acute and refractory migraine.
Administered intravenously in a structured clinical setting, DHE works by:
DHE infusion therapy is often considered for:
Because migraine infusion therapy involves potent medications, treatment is conducted in a medically supervised setting.
Before treatment, we evaluate:
DHE is not appropriate for everyone. Screening is essential.
Many patients experience improvement during or shortly after infusion.
Yes. Ketamine is commonly used as a rescue treatment for ongoing migraine attacks.
Ketamine works centrally on pain signaling rather than vascular constriction, making it effective when triptans fail.
Yes. Ketamine is often used for status migrainosus, when migraines persist for days.
Some patients improve after a single rescue infusion, while others benefit from a short series.
Ketamine is FDA-approved as an anesthetic and used off-label for migraine management under physician supervision.
Possible short-term effects include:
These typically resolve within hours.
No. You must arrange transportation home.
Not at this time. We do offer flexible monthly payment options through Wisetack.
If migraines are severe, prolonged, or no longer responding to medication, IV ketamine therapy may help provide relief.
Southern California Infusion Therapy offers the latest in innovative new treatments for chronic pain and mood disorders such as depression, anxiety, PTSD and OCD.
Copyright © 2026 SoCal Infusions | SoCal Infusions provides medical and mental health services under the supervision of licensed healthcare providers. The information on this website is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider with questions regarding your condition or care. Some treatments offered may be used off-label.
If you are experiencing an emergency, call 911 immediately. If you are in crisis or having suicidal thoughts, call 988 or 1-800-273-TALK (8255).